Dammarane Sapogenin PPT

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Reduce Chemo Toxicity, Improve Quality of Life, Extend Patient Survival.

> Dammarane sapogenin PPT (protopanaxatriol) is extracted and purified from Asian ginseng, and its pharmacological effect is 5-10 times as potent as its precursors Rh1 and Rg1, respectively.

> Facts of Cancer treatments:

. >90% of chemo patients experiences severe toxicity; . >50% of cancer patients die of chemo toxicity and its complications; . >80% of cancer patients have poor quality of life.

> Comprehensive studies from cell cultures, animal models and human trials prove that PPT not only possesses moderate anti-cancer activity and drug resistance reversal ability, but also:[1-5]

. Stimulates bone marrow proliferation in in-vitro cell culture, with an efficacy equivalent to G-CSF . Reduces toxicities of chemo drugs like cisplatin and cyclophosphamide on bone marrow (leukopenia, thrombocytopenia), down to under 18% . Resists Co60 radiation toxicity on bone marrow . Boosts lymphocyte responsiveness after chemo- and radio-therapies . Improves general health (body weight, food/water intake, etc) after chemo- and radio-therapies . Ameliorates intractable bone pain due to bone metastasis . Extends survival by >2-fold in 2/3 of patients . Improves quality of life in 3/4 of patients

> References:

1. Planta Med. 2011 Jan;77(2):133-40 2. Molecules. 2011 Dec 19;16(12):10619-30 3. Planta Med. 2003 Mar;69(3):235-40 4. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1308-14 5. Exp Biol Med (Maywood). 2011 Jun 1;236(6):729-35 back to blog